(WO/2008/063555) METHODS OF ENHANCING IMMUNE RESPONSE USING ELECTROPORATION-ASSISTED VACCINATION AND BOOSTING
- Biblio. Data
- Description
- Claims
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- Notices
- Documents
| Latest bibliographic data on file with the International Bureau | ||||||||||||
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| IPC: | A61K 39/00 (2006.01) | |||||||||||
| Applicants: | GENETRONICS, INC. [US/US]; 11494 Sorrento Valley Road, San Diego, CA 92121-1318 (US) (All Except US). MATHIESEN, Iacob [NO/NO]; 11494 Sorrento Valley Road, San Diego, CA 92121-1318 (US) (US Only). TJELLE, Elisabeth, Torunn [NO/NO]; 11494 Sorrento Valley Road, San Diego, CA 92121-1318 (US) (US Only). KJEKEN, Rune [NO/US]; 11494 Sorrento Valley Road, San Diego, CA 92121-1318 (US) (US Only). RABUSSAY, Dietmar [AT/US]; 11494 Sorrento Valley Road, San Diego, CA 92121-1318 (US) (US Only). LIN, Feng [CN/US]; 11494 Sorrento Valley Road, San Diego, CA 92121-1318 (US) (US Only). | |||||||||||
| Inventors: | MATHIESEN, Iacob; 11494 Sorrento Valley Road, San Diego, CA 92121-1318 (US). TJELLE, Elisabeth, Torunn; 11494 Sorrento Valley Road, San Diego, CA 92121-1318 (US). KJEKEN, Rune; 11494 Sorrento Valley Road, San Diego, CA 92121-1318 (US). RABUSSAY, Dietmar; 11494 Sorrento Valley Road, San Diego, CA 92121-1318 (US). LIN, Feng; 11494 Sorrento Valley Road, San Diego, CA 92121-1318 (US). | |||||||||||
| Agent: | CHAMBERS, Daniel, M.; Biotechnology Law Group, 527 N. Hwy. 101, Suite E, Solana Beach, CA 92075-1173 (US). | |||||||||||
| Priority Data: |
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| Title: | METHODS OF ENHANCING IMMUNE RESPONSE USING ELECTROPORATION-ASSISTED VACCINATION AND BOOSTING |
| Abstract: |  Disclosed are methods of enhancing immune responses. Such methods involve the administration of vaccine compositions to different tissues to elicit an enhanced immune response. The enhanced response arises from the vaccination and boosting route of administration in two separate patient tissues, for example, by first administering a priming vaccination into skin and later administering a boost vaccination in muscle. In each case, priming and boosting, the administration of the vaccine composition is preferably carried out using contemporaneous electroporation-assisted delivery of the antigenic agent. |
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